Key Takeaways
- Gabriel Otte co-founded Dinari, focusing on tokenizing real-world assets to bridge traditional finance and blockchain.
- Otte led Freenome as CEO, advancing AI-driven diagnostics for early cancer detection and precision medicine.
- With a software engineering and biotech background, Otte brings unique expertise to health tech and blockchain.
Who Is Gabriel Otte?
Gabriel Otte is an entrepreneur, software engineer, and researcher. He works at the crossroads of healthcare, artificial intelligence, and blockchain. He is the co-founder and CEO of Dinari, which turns real-world assets into digital tokens to connect traditional finance with decentralized systems. With experience in biotech and blockchain, Otte is known for using science and technology to solve real-world problems.
| Date | Milestone |
|---|---|
| December 2008 to August 2011 | Research assistant at Cornell University |
| June to December 2011 | Engineer at Glyde Corporation, Palo Alto |
| September 2014 | Co-founds Freenome and serves as its CTO |
| January 2016 | Becomes Freenome’s CEO, a role held until April 2021 |
| May 2018 | Becomes a partner at Healthcare Co-op |
| May 2025 | Dinari, co-founded by Otte, raises a $12.7 million Series A led by Hack VC and Blockchange Ventures |
| June 2025 | Dinari says it is the first company with U.S. approval to offer tokenized stocks |
| August 2026 | Dinari opens 724 tokenized U.S. stocks, including the whole S&P 500, to eligible U.S. investors and businesses |
Early Career and Academic Foundation
Gabriel Otte started his career as a Research Assistant at Cornell University from December 2008 to August 2011. During this time, he worked on projects that studied the connection between small blood vessel diseases and Alzheimer’s disease using specially bred mice. He also helped create a partly automated tracing program, showing his early interest in using computer tools in medical research.
Engineering Experience at Glyde
In mid-2011, Gabriel Otte entered the tech industry and worked as an Engineer at Glyde Corporation in Palo Alto, California. This job, which lasted from June to December 2011, gave him direct experience in software development and systems engineering and helped build the foundation for his later work in technology and health innovation.
Founding Freenome
In September 2014, Gabriel Otte co-founded Freenome, a biotech company focused on finding cancer early using artificial intelligence and machine learning. He first worked as the Chief Technology Officer (CTO), where he led the creation of key tools by combining biology and computer models.
In January 2016, he became the Chief Executive Officer (CEO), leading Freenome through important moments like raising money and forming key partnerships. From then until April 2021, Otte was a major part of Freenome’s growth into a top company in precision medicine. His leadership helped develop new ways to detect cancer early through blood tests and machine learning.
Supporting Community Health
While still leading Freenome, Gabriel Otte also became a Partner at Healthcare Co-op in May 2018, a role he still holds today. Based in the San Francisco Bay Area, this role shows his ongoing dedication to improving healthcare through new ideas and community-focused solutions. It adds to his work in biotechnology and health technology.
Entering Web3 – Founding Dinari
After leaving Freenome, Gabriel Otte moved into the blockchain world by co-founding Dinari, a financial technology startup that aims to connect traditional finance with decentralized technology.
Dinari focuses on turning real-world assets, like U.S. stocks, into digital tokens to make financial markets more open and accessible to people worldwide. His transition into Web3 is a natural step in his career—from using AI to solve medical problems to creating secure blockchain systems that could change how people access financial services.
Dinari Raises $12.7M to Tokenize U.S. Equities
On May 1, 2025, Dinari announced a $12.7 million Series A funding round, led by Hack VC and Blockchange Ventures, to bring U.S. equities onto the blockchain. This move aims to make traditional stocks more accessible to anyone, anywhere in the world, by turning them into digital tokens. The goal is to create a more open and inclusive financial system that allows people from all backgrounds to participate in the global market. This is a big step for Dinari as it continues to bridge the gap between traditional finance and decentralized technology. In June 2025, Dinari said it was the first company to secure U.S. approval to offer tokenized stocks. In August 2026, it opened 724 tokenized U.S. stocks, including the whole S&P 500, to eligible U.S. investors and businesses.
The Role of AI in Gabriel Otte’s Career
Artificial intelligence (AI) has played a key role in Gabriel Otte’s career. At Freenome, AI-powered tools were used to detect cancer early. Later, at Dinari, Otte applied AI to create blockchain-based financial solutions. His ability to combine AI with other technologies like blockchain and biotech makes him a leader in both fields. Otte focuses on AI’s potential to improve decision-making and automate processes, which is central to his approach to innovation.
Otte’s Vision for Blockchain and Finance
Gabriel Otte believes blockchain can change the way finance works. Through Dinari, he imagines a future where traditional financial systems are easier to access, more transparent, and open to everyone. By turning real-world assets like U.S. stocks into digital tokens, Otte wants to remove barriers to financial markets, allowing people worldwide to participate in the global economy. His work in Web3 and tokenization is paving the way for a new wave of financial innovation.
Gabriel Otte’s Mix of Biotech and Blockchain
Gabriel Otte’s career covers a wide range of fields, including biotech, healthcare, and blockchain, always showing his ability to combine technical skills with real-world solutions. From his early research work at Cornell to leading Freenome and co-founding Dinari, Otte shows how blending different fields of knowledge can change industries. As blockchain technology keeps growing, Otte’s influence is expected to increase, especially in how decentralized technology connects with the global economy.
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